Use of phage display biopanning as a tool to design CAR-T cells against glioma stem cells.

Marine Potez,Sebastian Snedal,Chunhua She,Jongmyung Kim, Konrad Thorner,Timothy H Tran,Maria Cecilia Ramello,Daniel Abate-Daga,James K C Liu

Frontiers in oncology（2023）

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摘要

These results exemplify the use of phage display biopanning for the isolation of GSC-targeting peptides, and their potential application in the development of novel cytotoxic therapies for GBM.

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关键词

CAR-T,N-cadherin,glioblastoma,glioma stem cells,novel binding domains,peptides,phage display biopanning

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