Thymic function and survival at advance ages in nursing home residents from Southern Italy.

Immunity & ageing : I & A(2023)

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摘要
Thymic function failure is an independent predictor of mortality among elderly nursing home residents. sjTREC represents a biomarker of effective ageing as its blood levels could anticipate individuals at high risk of negative health outcomes. The identification of these subjects is crucial to manage older people's immune function and resilience, such as, for instance, to plan more efficient vaccinal campaigns in older populations.
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关键词
Advanced age,C-reactive protein (CRP),Immunoageing,Immunosenescence,Mortality,Nursing home,Survival,T-cell receptor rearrangement excision circles (sjTRECs),thymus
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