Pharmacokinetics and pharmacodynamics of adult dolutegravir tablets in treatment-experienced children with HIV weighing at least 20 kg.

Charles Martyn-Dickens, Oluwayemisi Ojewale, Eugenia Sly-Moore, Albert Dompreh,Anthony Enimil, Aikins Kofi Amissah,Dennis Bosomtwe, Augustina Frimpong Appiah, Ama D Sarfo, Theresah Opoku, Priscilla Asiedu, Stephen K Dong, Isaac Kusi-Amponsah,Nicole Maranchick,Charles A Peloquin,Sampson Antwi,Awewura Kwara

AIDS (London, England)（2023）

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摘要

The higher dolutegravir exposure in our study population suggests that further studies and close monitoring should investigate the adverse effects of dolutegravir in more children and in the long term.

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关键词

adult tablets, children, dolutegravir, pharmacodynamics, pharmacokinetics, treatment-experienced

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