Dynapenic Abdominal Obesity Increases Risk for Falls Among Adults Aged 50 Years: A Prospective Analysis of the Irish Longitudinal Study on Ageing

Lee Smith, Guillermo F. Lopez Sanchez,Nicola Veronese, Pinar Soysal,Masoud Rahmati, Louis Jacob,Karel Kostev, Josep Maria Haro,Abdullah Ahmed Alghamdi, Laurie Butler,Yvonne Barnett, Helen Keyes,Mark A. Tully, Jae Shin,Ai Koyanagi

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES(2024)

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摘要
Background There is a scarcity of studies examining the longitudinal relationship between dynapenic abdominal obesity (DAO; ie, impairment in muscle strength and high waist circumference) and future fall risk. Therefore, we aimed to investigate the prospective association between DAO at baseline and falls occurring during 2 years of follow-up in a nationally representative sample of middle-aged and older individuals from Ireland. Methods Data from 2 consecutive waves of the Irish Longitudinal Study on Ageing survey were analyzed. Dynapenia was defined as handgrip strength of 88 cm for women and >102 cm for men. DAO was assessed at Wave 1 (2009-2011) and was defined as having both dynapenia and abdominal obesity. Falls occurring between Wave 1 and Wave 2 (2012-2013) were self-reported. Multivariable logistic regression analysis was conducted. Results Data on 5 275 individuals aged >= 50 years were analyzed (mean [standard deviation {SD}] age 63.2 [8.9] years; 48.8% males). After adjustment for potential confounders, compared to no dynapenia and no abdominal obesity at baseline, DAO was significantly associated with 1.47 (95% confidence interval [CI]: 1.14-1.89) times higher odds for falls at 2-year follow-up. Dynapenia alone (odds ratio [OR] = 1.08; 95% CI: 0.84-1.40) and abdominal obesity alone (OR = 1.09; 95% CI: 0.91-1.29) were not significantly associated with falls at follow-up. Conclusions DAO increased the risk for falls among middle-aged and older adults in Ireland. Interventions to prevent or reverse DAO may be beneficial for fall reduction.
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关键词
Abdominal obesity,Dynapenia,Dynapenic abdominal obesity,Falls,Older adults,TILDA
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