IL-37 alleviates TNF-α-induced pyroptosis of rheumatoid arthritis fibroblast-like synoviocytes by inhibiting the NF-κB/GSDMD signaling pathway.

Chunfeng Ren,Jie Chen, Qincheng Che,Qian Jia,Hongqin Lu,Xiaoyan Qi,Xiaojie Zhang,Qiang Shu

Immunobiology（2023）

引用 2|浏览1

暂无评分

摘要

IL-37 alleviates TNF-α-induced pyroptosis of RA FLSs by inhibiting NF-κB/GSDMD signaling. Additionally, our data revealed a novel mechanism for IL-37 in RA FLSs, suggesting a new potential therapy for IL-37 to treat RA.

查看译文

关键词

Fibroblast-like synoviocytes,IL-37,NF-κB,Pyroptosis,Rheumatoid arthritis,TNF-α

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要