AdipoAI suppresses osteoclastogenesis by activating AdipoR1/APPL1: An in vivo experimental study in diabetes-associated peri-implantitis.

Wei Qiu,Zehao Chen,Zhaodan Wang,Yuanting Chen,Kaiqi Luan,Kaiying Zhang,Hongwen Yu,Qisheng Tu,Jake Chen,Hongle Wu,Fuchun Fang

Clinical oral implants research（2023）

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摘要

AdipoAI suppressed osteoclastogenesis in diabetes-associated peri-implantitis by inhibiting the NF-κB and Wnt5a-Ror2 pathways via the AdipoR1/APPL1 axis.

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关键词

AdipoAI,NF-κB,Wnt5a,adiponectin,diabetes,osteoclast,peri-implantitis

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