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Serum Tryptophan Metabolites are Associated with Erosive Hand Osteoarthritis and Pain: Results from the DIGICOD Cohort.

Marie Binvignat,Patrick Emond,Francois Mifsud,Brenda Miao,Alice Courties,Antoine Lefèvre,Emmanuel Maheu,Michel D Crema,David Klatzmann,Margreet Kloppenburg,Pascal Richette,Atul J Butte,Encarnita Mariotti-Ferrandiz,Francis Berenbaum,Harry Sokol,Jérémie Sellam

Osteoarthritis and cartilage（2023）

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摘要
Tryptophan metabolites disturbance is associated with erosive HOA and pain and emphasize the role of low-grade inflammation and gut dysbiosis in HOA.
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关键词
Erosive hand osteoarthritis,Gut Microbiome,Hand Osteoarthritis,Metabolomic,Pain,Symptoms
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