Connection of Dried Blood Spot Proteomic Composition Dynamics and Heart Rate Variability in 3-day Female Dry Immersion

For the first time, the peculiarities of the blood proteomic composition depending on the predominance of the vegetative regulation type were analyzed under the conditions of dry immersion in women volunteers (age 30.17 ± 5.5 years, height 1.66 ± 0.1 m, weight 62.05 ± 8.4 kg, BMI 22.39 ± 2.2 kg/m 2 ) with a natural menstrual cycle. The experiment “NAIAD-2020” was carried out at the Institute of Biomedical Problems (Moscow, Russia). It has been shown that under normal motor activity (in baseline studies), in individuals with various modulating types of autonomic influences, energy expenditure is provided mainly by carbohydrate metabolism, which has genetic features in the implementation of the pentose pathway. During dry immersion, with minimal motor activity, energy expenditure sharply decreases, leveling out vagus-mediated differences between the groups. On the second day of the recovery period, processes related to the functions of heat shock proteins and excosomes were noted.