Supplemental Figures from Eradication of Acute Myeloid Leukemia with FLT3 Ligand–Targeted miR-150 Nanoparticles

Supplemental Figure 1. Construction of G7-FLT3L dendrimers and their uptake ratio in AML cells. Supplemental Figure 2. G7 PAMAM dendrimers efficiently complex small, single stranded oligonucleotides. Supplemental Figure 3. G7-FLT3L-miR-150 nanoparticles repressed expression of direct or indirect target genes of miR-150 in vitro. Supplemental Figure 4. The specific targeting and inhibitory effect of G7-Flt3L-miR-150 nanoparticles to FLT3-overexpressing AML cells in vitro. Supplemental Figure 5. In vivo uptake and function of G7-Flt3L-miR-150 nanoparticles. Supplemental Figure 6. Analysis of the potential influence of the nanoparticles on hematopoietic system in normal mice.