Supplementary Figure 2 from Tumor Suppressor Alterations Cooperate to Drive Aggressive Mesotheliomas with Enriched Cancer Stem Cells via a p53–miR-34a–c-Met Axis

Craig W. Menges,Yuwaraj Kadariya,Deborah Altomare,Jacqueline Talarchek,Erin Neumann-Domer,Yue Wu,Guang-Hui Xiao,Irina M. Shapiro,Vihren N. Kolev,Jonathan A. Pachter, Andres J. Klein-Szanto,Joseph R. Testa

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PDF - 939K, Spheroids and metastatic MM tumors harbor CSC populations. A) Tumor spheroids from Nf2 (+/-);p16/p19 (+/-) mice stained for Oct 3/4 and Nanog. B) Metastatic tumors from the experimental lung metastasis assay stained for CSC markers beta-catenin, Nanog, Oct 3/4 and Sox2.

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