Supplementary Methods from MDM2 Small-Molecule Antagonist RG7112 Activates p53 Signaling and Regresses Human Tumors in Preclinical Cancer Models

Christian Tovar,Bradford Graves,Kathryn Packman,Zoran Filipovic, Brian Higgins Mingxuan Xia,Christine Tardell,Rosario Garrido,Edmund Lee,Kenneth Kolinsky, Kwong-Him To,Michael Linn,Frank Podlaski,Peter Wovkulich,Binh Vu,Lyubomir T. Vassilev

crossref（2023）

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PDF file - 136K, Includes HTRF, cell growth/viability, apoptosis assays and biacore, crystal structure and animal studies. Also includes supplemental references.

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