Supplementary figures from Preclinical Anticancer Efficacy of BET Bromodomain Inhibitors Is Determined by the Apoptotic Response

crossref(2023)

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This file contains six supplementary figures: Figure S1 (related to Figure 1) provides additional characterization of the BETi tolerant cell lines; Figure S2 (related to Figure 1) provides additional information regarding gene expression changes in the BETi tolerant cell lines; Figure S3 (related to Figure 2) provides further support for the importance of BCL2 and BCL2L1 expression in the BETi tolerant cell lines; Figure S4 (related to Figures 3 and 4) quantifies Figure 3C, and provides supporting data and additional analysis for BCL2/BCL2L1/BAD as predictive biomarkers; Figure S5 (related to Figure 4) provides supporting data for BCL2 family expression as predictive biomarkers; Figure S6 (related to Figure 4) shows that BCL2/BCL2L1 protein expression can serve as predictive biomarkers for BETi response.

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