Multiomics Analysis of Plasma Proteomics and Metabolomics of Steroid Resistance in Childhood Nephrotic Syndrome Using a "Patient-Specific" Approach.

Sagar Bhayana,Yue Zhao,Michael Merchant,Timothy Cummins,Julie A Dougherty, Yu Kamigaki,Wimal Pathmasiri,Susan McRitchie,Laura H Mariani,Susan Sumner,Jon B Klein,Lang Li,William E Smoyer

Kidney International Reports（2023）

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摘要

These studies confirmed that a novel "patient-specific" bioinformatic approach can integrate disparate omics datasets and identify candidate SRNS biomarkers not observed by separate proteomic or metabolomic analysis.

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关键词

childhood nephrotic syndrome,plasma proteomics,metabolomics,steroid resistance,multiomics analysis,patient-specific

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