Neutralizing Antibody Response of the Wild-Type/Omicron BA.1 Bivalent Vaccine as the Second Booster Dose against Omicron BA.2 and BA.5

Hitoshi Kawasuji,Yoshitomo Morinaga,Hideki Tani,Yumiko Saga,Hiroshi Yamada,Yoshihiro Yoshida,Yusuke Takegoshi,Makito Kaneda,Yushi Murai,Kou Kimoto,Akitoshi Ueno,Yuki Miyajima,Kentaro Nagaoka,Chikako Ono,Yoshiharu Matsuura,Hideki Niimi,Yoshihiro Yamamoto

Microbiology Spectrum（2023）

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摘要

Although Omicron BA.1-containing bivalent vaccines have been authorized, real-world data validating their safety and antibody responses remain scarce. We conducted a prospective longitudinal study to assess the safety, immunogenicity, and reactogenicity of the second booster dose with the Omicron BA.1 bivalent vaccine in health care workers.

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关键词

bivalent vaccine,second booster dose,wild-type/omicron

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