Cobalt-catalyzed Dehydrogenative Cross-Coupling Reaction: Selective Access to Dihydrosiloxanes, Hydrosiloxanes and Functionalized Silsesquioxanes

Disclosed is a mild, scalable, and chemoselective cross-dehydrogenative functionalization protocol for the construction of Si-O-Si moieties under cobalt catalysis. The reaction has a broad scope and can be used to synthesize a wide range of silicon building blocks, including challenging dihydrosiloxanes and func-tionalized silsesquioxanes. Most importantly, the results are placed into context by benchmarking with state-of-the-art methods. Remarkably, the utilized PNP-Co catalyst enables the development of further synthetic strategies such as a one-pot sequential silanolysis/alcoholysis process or unprecedented dehy-drocoupling reaction between germanol and hydrosilane.(c) 2023 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).