Achondroplasia Natural History Study (CLARITY): 60-Year Experience in Orthopedic Surgery from Four Skeletal Dysplasia Centers
Orphanet journal of rare diseases(2023)
摘要
The purpose of this study was to describe the frequency and risk factors for orthopedic surgery in patients with achondroplasia. CLARITY (The Achondroplasia Natural History Study) includes clinical data from achondroplasia patients receiving treatment at four skeletal dysplasia centers in the United States from 1957 to 2018. Data were entered and stored in a Research Electronic Data Capture (REDCap) database. Information from one thousand three hundred and seventy-four patients with achondroplasia were included in this study. Four hundred and eight (29.7
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关键词
Achondroplasia,Spinal stenosis,Thoracolumbar kyphosis,Genu varum
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