211P Chemotherapy delivery time affects anti-lymphoma treatment outcome in a sex-dependent manner

Chronotherapy is a drug intervention at specific times of the day to optimize efficacy and minimize adverse effects. Although chronochemotherapy has been proven to be effective in solid tumors, its value in hematologic malignancy remains unknown. In this study, we tried to identify a chronotherapeutic effect and underlying mechanism of immunochemotherapy in diffuse large B cell lymphoma (DLBCL) patients.