32P Tumor Growth Inhibition Effect of PLAG by Regulation of Neutrophil Infiltration in ICI Insensitivity B16F10 Melanoma

Malignant melanoma (MM) is a representative tumor with a low survival rate due to its early diagnosis difficulty and poor treatment efficacy. Melanoma usually promotes its growth via tumor-infiltrating neutrophils (TINs), which inhibit the activation of immune cells that prevent cancer cells such as cytotoxic T lymphocytes. Therefore, the best option for MM treatment is to prevent excessive neutrophil infiltration into cancer lessons.