418. STRATEGIES FOR OLIGOMETASTATIC AFTER CURATIVE RESECTION OF ESOPHAGEAL CANCER

Abstract The recurrence rates in patients with esophageal cancer who are treated by curative esophagectomy is reported to be 29-43%. Recently, the concept of oligometastasis recurrence (OLR) has gained attention. To clarify the relationship between treatment strategy and prognosis of patients with OLR after esophagectomy. We included 124 patients with recurrence among 446 patients who underwent esophagectomy for esophageal cancer. OLR was defined as five or fewer recurrences in a single organ or five or fewer recurrences in a single lymph node. Patients were divided into two groups: OLR and non-OLR group. Recurrence within 6 months after surgery was defined as early recurrence. The relationship between early recurrence and prognosis was examined. We focused on liver and lung metastases and examined treatment methods and prognosis. Of the recurrence patients, 40 (32%) were in the OLR group and 84 (78%) were in the non- OLR group. The overall survival was 49 months in the OLR group and 17 months in the non-OLR group (p < 0.001). Survival after recurrence was 26 months in the OLR group and 6 months in the non-OLR group (p < 0.001). In comparison of the early relapse and non-early relapse groups, both OS and survival after recurrence tended to be worse in the early relapse group (p = 0.05). The prognosis was better in the lymph node recurrence group and worse in the liver recurrence group (p = 0.05). Oligometastasis is related to prognosis in patients with recurrence after esophagectomy, and patients with early recurrence or liver recurrence may have a poor prognosis.