Flexible synthesis to deliver relevant evidence for decision-making

The use of systematic reviews to collate and summarise evidence is considered one of the great intellectual achievements of recent times. Evidence synthesis has had far-reaching impacts and has helped to inform decision-making in multiple fields. However, it also faces three problems: (i) reviews cannot be relevant to everyone, hampering decision-making, (ii) multiple conflicting review are often produced, and (iii) reviews can become out-of-date rapidly. Here we present a solution to these problems that we term 'dynamic meta-analysis.' With a tool we have developed, users can filter and weight evidence depending on their interests to produce analyses that are highly relevant to their needs.