Efficacy of virtually-delivered Qigong/Tai Chi for depression in middle- and older-age adults with bipolar disorder (QT-BD): A pilot randomized controlled trial during the COVID-19 pandemic

•Virtual Qigong/Tai Chi vs active control RCT for depression in bipolar disorder.•Participants were middle-aged and older adults with bipolar disorder.•No statistically significant reductions in depressive symptoms in both groups.•Five point MADRS reduction in intervention subgroup with baseline MADRS ≥10.•QT may be a feasible and efficacious intervention for reducing depressive symptoms.