Senescence markers in subcutaneous preadipocytes differ in childhood- versus adult-onset obesity before and after weight loss.

Jessica Murphy,Bjorn T Tam,James L Kirkland,Tamara Tchkonia,Nino Giorgadze,Tamar Pirtskhalava,Michael A Tsoukas,José A Morais,Sylvia Santosa

Obesity (Silver Spring, Md.)（2023）

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摘要

These results provide preliminary evidence that females with CO have an accelerated preadipocyte aging state that improves with weight loss in terms of DNA damage but not senescence.

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关键词

subcutaneous preadipocytes,obesity

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