Synthesis of -Substituted Alkenylammonium Salts through Suzuki-Miyaura and Sonogashira Coupling

Alkenylammonium salts are a unique class of compounds, wherein an electron-withdrawing ammonio group is attached to an olefin. Although these salts are structurally simple, the synthesis of alpha-substituted alkenylammonium salts has been sparsely explored. Herein we report the synthesis of alpha-aryl and alpha-alkynylated alkenylammonium salts through Suzuki- Miyaura and Sonogashira coupling.