Electrochemical oxidation-induced benzylic C(sp3)–H functionalization towards the atom-economic synthesis of oxazole heterocycles

A unique electrochemical four-component reaction of terminal alkynes, (thio)xanthenes, nitriles, and water has been established in the absence of any catalyst or external oxidant. This electrochemical reaction features high atom economy and mild conditions, affording oxazole derivatives in moderate to good yields.