Mitochondrial Ca2+ signaling and Alzheimer's disease: Too much or too little?

Paloma Garcia-Casas,Michela Rossini,Riccardo Filadi,Paola Pizzo

Cell Calcium（2023）

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摘要

•Mitochondrial Ca2+ signaling is altered in Alzheimer's disease (AD).•Mitochondrial Ca2+ influx/efflux machinery is altered in AD models.•Alterations of ER-mitochondria contacts perturb mitochondrial Ca2+ signal in AD.

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mitochondrial ca2+,alzheimer

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