Effect of gentamicin on CD3+ T-lymphocyte proliferation for treatment of equine recurrent uveitis: An in vitro study.

Hannah L Smith,Alix K Berglund,James B Robertson,Lauren V Schnabel,Richard J McMullen,Brian C Gilger,Annie Oh

Veterinary ophthalmology（2023）

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摘要

Gentamicin had no effect on equine peripheral blood CD3+ T-lymphocyte cell viability and proliferation in concentrations ranging from "safe" to "retinotoxic" in relation to intravitreal injection volumes. Low-dose intravitreal gentamicin may not suppress the Th1- and Th17-mediated immune response.

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关键词

autoimmune disease, equine recurrent uveitis, gentamicin, horse, immunology, intravitreal injection

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