Strategies to prevent water soluble drug leakage from nanovesicles in blood circulation: A coarse-grained molecular study

Yun Hao Feng,Wei Xin Guo,Xiaobin Li,Jiahui Liu,Vahideh Nosrati-Siahmazgi,Maryam Toolabi,Wen Min Fei,Yong Cui,Bo Zhi Chen,Mohammad-Ali Shahbazi,Li Juan Zhang,Can Yang Zhang,Xin Dong Guo

Chemical Engineering Science（2023）

引用 0|浏览12

暂无评分

摘要

•Two strategies to prevent drug leakage were studied by coarse-grained molecular simulation.•CHolSH can fill the holes in the hydrophobic layer to avoid drug leakage.•AuNP shows “physically cross-link” with hydrophobic layer to inhibit drug leakage.•Janus AuNP possesses higher dispersibility than randomly modified AuNP.

查看译文

关键词

soluble drug leakage,nanovesicles,blood circulation,coarse-grained

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要