Abnormal auditory brainstem responses in an animal model of autism spectrum disorder

Hearing Research（2023）

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摘要

•In utero VPA exposure is an animal model of ASD.•VPA-exposed rats have fewer auditory brainstem neurons and abnormal connectivity.•VPA-exposed rats have elevated thresholds and longer latency ABR waves.•ABR differences improve with age but remain evident near threshold.•ABR screening may be reveal more consistent changes in the neonatal period.

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关键词

abnormal auditory brainstem responses,autism spectrum disorder,animal model

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