Impact of insufficient recovery of cerebral blood flow due to partial reperfusion on the pathophysiology of ischemic stroke in mice

Neuroscience Letters(2023)

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摘要
•Pathophysiology of partial reperfusion was different from permanent occlusion.•Partial reperfusion delayed neuronal degeneration with increased apoptosis.•IgG extravasation was inhibited in partial reperfusion.•Intravenous FITC-dextran could reach the infarct region with leakage.•il6 and il1β mRNA was less produced in partial reperfusion.
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关键词
ischemic stroke,cerebral blood flow,partial reperfusion,pathophysiology
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