ID: 212826 Investigation of 10KHz Spinal Cord Stimulation on Small Fiber Painful Diabetic Neuropathy (PDN)

A large multicenter RCT1 recently demonstrated that spinal cord stimulation (SCS) at 10 kHz provides effective pain relief for patients with painful diabetic neuropathy (PDN). These outcomes remain durable to 24 months.2 Patient-reported outcomes suggest profound improvements in pain, function, and quality of life with 10kHz SCS in PDN patients, but more objective quantitative measures of nerve pathology and function can confirm these clinical outcomes and suggest the mechanism of action for the observed clinical improvements.