Exposure to manganese (II) chloride induces developmental toxicity, oxidative stress and inflammatory response in Marine medaka (Oryzias melastigma) embryos

Aquatic Toxicology(2023)

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摘要
•MnCl2 exposure causes developmental toxicity in Oryzias melastigma embryos.•Heart might be an important target organ of Mn during the fish early-life stage.•MnCl2 exposure induces oxidative stress in O. melastigma embryos.•The expression levels of stress- and inflammation-related genes were significantly upregulated after MnCl2 exposure.
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关键词
manganese,developmental toxicity,marine medaka,embryos,oxidative stress
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