Giant juvenile fibroadenomas with and without prominent pseudoangiomatous stromal hyperplasia (PASH)-like change: clinicopathological and molecular characteristics.

Julie M Jorns,Ayesha Farooq,Andrii Puzyrenko,Jason Jarzembowski,Aye Aye Thike,Nur Diyana Md Nasir,Cedric Chuan Young Ng,Wei Liu,Jing Yi Lee,Abner Herbert Lim,Peiyong Guan,Bin Tean Teh,Puay Hoon Tan

Histopathology（2023）

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摘要

Gene mutations along more advanced phases of the proposed FEL pathogenetic pathway in GJFA are unusual, and suggest a mechanism for more aggressive growth in these tumours.

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关键词

breast, fibroadenoma, fibroepithelial, giant juvenile fibroadenoma, next generation sequencing, PASH, pseudoangiomatous stromal hyperplasia

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