Application Value of Serum Neurofilament Light Protein for Disease Staging in Huntington's Disease.

Xiao-Yan Li,Yu-Feng Bao,Juan-Juan Xie,Bin Gao,Shu-Xia Qian,Yi Dong,Zhi-Ying Wu

Movement disorders : official journal of the Movement Disorder Society（2023）

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摘要

Although sNfL levels are independent of disease stages in manifest HD, it is still an optimal indicator for predicting disease onset and has potential use as a surrogate biomarker of treatment effect in clinical trials. © 2023 International Parkinson and Movement Disorder Society.

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Huntington's disease, neurofilament light protein, disease staging, 7, 0 T MRI, longitudinal study

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