One versus two courses of antenatal corticosteroids in pregnancies at risk of preterm birth: A secondary analysis of the MACS trial: One versus two courses of antenatal corticosteroids.

Neonatal mortality and severe morbidities, including severe respiratory distress syndrome were not improved by a second course of antenatal corticosteroids. Policy makers need to be thoughtful when recommending a second course of antenatal corticosteroids and consider what benefits are hoped to be gained from its administration not only short-term but also long-term.