Tolerability and beneficial effects of sacubitril/valsartan on systemic right ventricular failure.

Marieke Nederend,Philippine Kiès,Madelien V Regeer,Hubert W Vliegen,Bart Ja Mertens,Daniëlle Robbers-Visser,Berto J Bouma,Laurens F Tops,Martin J Schalij,Monique R M Jongbloed,Anastasia D Egorova

Heart (British Cardiac Society)（2023）

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摘要

Treatment with sacubitril/valsartan was associated with a low rate of adverse effects in this adult sRV cohort. Persisting improvement in 6-minute walking test distance, NT-proBNP levels and echocardiographic parameters of sRV function was observed in an on-treatment analysis and showed no differential response based on sex or anatomy.

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关键词

heart failure, systolic, pharmacology, heart defects, congenital, transposition of great vessels

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