Prevalence of intracranial aneurysms in Marfan syndrome

In a large, single-center experience over 20 years, we identified patients with confirmed MFS who underwent intracranial imaging. Prevalence of IA our experience was 7.1%. There were no patient or aortic characteristics found to be significantly associated with IA, however this may be due to the small number of aneurysms. While this is higher than historically reported prevalence in the general population, a collection of experiences from multiple institutions will likely be required to truly define the risk of IA in MFS, and to determine whether screening is warranted.