Endocardial Fibroelastosis as an Independent Predictor of Atrioventricular Valve Rupture in Maternal Autoimmune Antibody Exposed Fetus: A Systematic Review with Clinicopathologic Analysis.

Monika Kantilal Kotecha,Khurshid Merchant, Charmaine Jiahui Chan,Jonathan Tze Liang Choo,Krishna Revanna Gopagondanahalli,Dyan Zhewei Zhang,Teng Hong Tan,Sreekanthan Sundararaghavan

Diagnostics (Basel, Switzerland)（2023）

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摘要

Atrioventricular valve rupture in neonatal lupus is rare. A majority of patients with valve rupture had antenatally detected endocardial fibroelastosis in the valvar apparatus. Appropriate and expedited surgical repair of ruptured atrioventricular valves is feasible and has a low mortality risk. Rupture of both atrioventricular valves occurring at close intervals carries a high mortality risk.

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neonatal lupus, maternal autoantibodies, endocardial fibroelastosis, complete heart block, anti-Ro, SSA antibodies, anti La, SSB antibodies, mitral valve rupture, tricuspid valve rupture

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