Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.

Qiuyuan Shao,Chunming Jiang,Qingyan Zhang,Jing Liu,Bo Jin,Min Zhao,Yangyang Xia

The journal of gene medicine（2023）

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摘要

This study demonstrated that knockdown of AK142426 suppressed M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun, suggesting that AK142426 might be a promising therapeutic target for patients of peritoneal fibrosis.

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关键词

AK142426, c-Jun, inflammation, M2 macrophage polarization, peritoneal fibrosis

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