MERS-CoV‒Specific T-Cell Responses in Camels after Single MVA-MERS-S Vaccination.

Christian Meyer Zu Natrup, Lisa-Marie Schünemann,Giulietta Saletti,Sabrina Clever,Vanessa Herder,Sunitha Joseph, Marina Rodriguez,Ulrich Wernery,Gerd Sutter,Asisa Volz

Emerging infectious diseases（2023）

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摘要

We developed an ELISPOT assay for evaluating Middle East respiratory syndrome coronavirus (MERS-CoV)‒specific T-cell responses in dromedary camels. After single modified vaccinia virus Ankara-MERS-S vaccination, seropositive camels showed increased levels of MERS-CoV‒specific T cells and antibodies, indicating suitability of camel vaccinations in disease-endemic areas as a promising approach to control infection.

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关键词

camels,mers-cov,t-cell,mva-mers-s

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