Exploring the potential mechanism of action of ursolic acid against gastric cancer and COVID-19 using network pharmacology and bioinformatics analysis.

This study found that in patients with gastric cancer and COVID-19, UA may bind to ACE2, regulate core targets such as PARP1 and MAPK14, and the PI3K/Akt signaling pathway, and participate in antiinflammatory, anti-oxidation, anti-virus, and immune regulation to exert therapeutic effects.