Serum Starvation Induces Matrix Metalloproteinase 9 Expression in Nasopharyngeal Carcinoma Cells Through the ERK-AP1 Pathway In Vitro .

Yen-Ting Wu,Chung-Chi Hsu,Bu-Miin Huang,Yun-Ching Chang,Cheng-Han Lin,Yu-Yan Lan

Anticancer research（2023）

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摘要

Serum starvation could up-regulate MMP9 expression in NPC cells, contributing to NPC invasion. Therefore, serum starvation may promote malignancy of NPC cells but also support MMP9 as a potential therapeutic target to prevent NPC cell invasion and metastasis.

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关键词

Serum starvation, nasopharyngeal carcinoma, matrix metalloproteinase 9, cell invasion

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