The let-7b-5p, miR-326, and miR-125a-3p are associated with left ventricular systolic dysfunction in post-myocardial infarction.

Raquel Costa Silva Dantas-Komatsu,Marina Sampaio Cruz,Paula Paccielli Freire,Rosiane Viana Zuza Diniz,Raul Hernandes Bortolin,Otávio Cabral-Marques,Kamilla Batista da Silva Souza,Mario Hiroyuki Hirata,Rosario Dominguez Crespo Hirata,Bruna Zavarize Reis,Igor Jurisica,Vivian Nogueira Silbiger,Andre Ducati Luchessi

Frontiers in cardiovascular medicine（2023）

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摘要

LVSd alters the expression of let-7b-5p, miR-326, and miR-125a-3p in PBMC from post-STEMI, indicating their potential involvement in the cardiac dysfunction physiopathology and highlighting these miRNAs as possible LVSd biomarkers.

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关键词

miRNA, PBMC, myocardial infarction, left ventricular systolic dysfunction, heart failure, enrichment analysis

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