Healthcare professionals' knowledge, confidence and perceptions of pharmacogenomics in primary care and pain management.

To assess knowledge, confidence and perceptions of healthcare professionals specializing in primary care and pain management at Brigham and Women's Hospital, related to clinical pharmacogenomics (PGx). A 25-question online survey was distributed to 328 Brigham and Women's Hospital clinicians for analysis. Thirty-four clinicians completed the survey. Respondents had minimal experience with PGx and limited awareness of PGx resources. Although respondents expressed belief that PGx has utility to improve medication-related patient outcomes, many lack confidence to apply PGx results to their practice. For clinical drug-gene questions relevant to primary care and/or pain management, respondents scored poorly. More clinician education is needed for appropriate utilization of PGx in clinical practice as it pertains to primary care and pain management.