Treatment of Early Glottic cancer with Transoral Laser Microsurgery: An Australian Experience
Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India(2022)
摘要
Introduction Early laryngeal carcinomas may be treated by transoral laser microsurgery (TLM) or external beam radiotherapy. We review our experience of surgical treatment of laryngeal pre-malignant and malignant lesions over the past 15 years in a high-volume head neck unit. Methods A review of a prospective patient database of patients with laryngeal SCC, who were treated with CO 2 TLM between 2004 and 2019 was carried out. Results 83 patients with a mean age of 67.7 (SD: 10.6) years underwent primary curative TLM for T1a/b SCC. 5-year overall survival was 93.2% (95%CI 86.9–100%), disease free survival was 86.0% (95%CI 78.1–94.6%), locoregional control was 91.2% (95%CI: 85.1–97.7%) and larynx preservation rate of 95.1% at 5 years. Conclusion TLM is an excellent treatment modality for T1 early glottic SCC, with excellent locoregional control and disease-free survival. It is minimally invasive, outpatient-based, and cost-effective procedure preserving upper aerodigestive tract dysfunction for all activities of daily living.
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关键词
transoral laser microsurgery,early glottic cancer
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