Dynamics and consequences of nutrition-related microbial dysbiosis in early life: study protocol of the VITERBI GUT project.

Jeanne Tamarelle,Margaux M Creze,Vanthanom Savathdy,Sengrloun Phonekeo,Jordyn Wallenborn,Latsamy Siengsounthone,Günther Fink,Peter Odermatt,Sengchanh Kounnavong,Somphou Sayasone,Pascale Vonaesch

Frontiers in nutrition（2023）

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摘要

We expect the VITERBI GUT project to contribute to the emerging literature linking the early life microbiota, epigenetic changes and growth/metabolic health. We also expect this project to give new (molecular) insights into the mechanisms linking malnutrition-induced early life dysbiosis and metabolic health in later life, opening new avenues for microbiota-engineering using microbiota-targeted interventions.

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关键词

overnutrition, undernutrition, metabolic syndrome, epigenetics, microbiota inheritance, microbial succession, Lao PDR, maternal and child health

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