Association of Body Mass Index and Abdominal Obesity with Incidence of Atrial Fibrillation in Heart Failure with Preserved Ejection Fraction.

Xinyi Huang,Xiao Liu, Yuan Jiang,Zhengyu Cao,Maoxiong Wu,Zhiteng Chen,Runlu Sun,Peng Yu,Jianyong Ma,Wengen Zhu,Yangxin Chen,Guifu Wu,Yuling Zhang,Jingfeng Wang

Current medicinal chemistry（2023）

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摘要

Abdominal obesity was associated with increased AF incidence (aHR: 1.70; 95% CI: 1.04-2.77), and AF incidence rose by 18% per centimeter in circumference (aHR: 1.18; 95% CI: 1.04-1.34). Obesity and abdominal obesity increase the incidence of AF in HFpEF patients. Further studies need to determine whether there is a difference in AF in response to spironolactone across obese HFpEF pheno groups.

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