Characterization of pain-related behaviors and gene expression profiling of peripheral sensory ganglia in a mouse model of acute ankle sprain.

Yushuang Pan,Qimiao Hu,Yunqin Yang,Huimin Nie,Chengyu Yin,Huina Wei,Yan Tai,Boyu Liu,Zui Shen,Xiaofen He,Jianqiao Fang,Boyi Liu

Frontiers in behavioral neuroscience（2023）

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摘要

Our study found LAS model mice may be used as a preclinical animal model for screening novel targets or therapies for ankle sprain. Thus, the study may further help to understand molecular mechanisms contributing to ankle sprain-induced pain.

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关键词

peripheral sensory ganglia,acute ankle,gene expression,gene expression profiling,pain-related

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