Comparative efficacy and safety of Gla-300 versus IDegAsp in insulin-naïve people with type 2 diabetes mellitus uncontrolled on oral anti-diabetics.

Robert Ritzel,Sujoy Ghosh,Rifat Emral,Rachid Malek,Longyi Zeng, Maria Aileen Mabunay,Wolfgang Landgraf,Patricia Guyot,Paul Serafini,Divya Pushkarna,Rayaz A Malik

Diabetes, obesity & metabolism（2023）

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摘要

In insulin-naïve patients with T2D inadequately controlled on OADs, commencing Gla-300 shows a comparable HbA1c reduction, but with significantly less weight gain and a lower incidence of any and confirmed hypoglycaemia compared with commencing IDegAsp.

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关键词

efficacy, indirect treatment comparison, insulin degludec-insulin aspart, insulin glargine, meta-analysis, safety

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