Severe Hepatopathy in National Wilms Tumor Studies 3-5: Prevalence, Clinical Features, and Outcomes After Reintroduction of Chemotherapy.

Natanja Oosterom,Saskia L M Gooskens,Lindsay A Renfro,Elizabeth J Perlman,Marry M van den Heuvel-Eibrink,Thomas E Hamilton,Daniel M Green,Paul E Grundy,Najat C Daw,James I Geller,Jeffrey S Dome,Conrad V Fernandez,Elizabeth A Mullen

Journal of clinical oncology : official journal of the American Society of Clinical Oncology（2023）

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摘要

The incidence of SH on NWTS 3-5 was low; many had associated severe thrombocytopenia. Careful reintroduction of chemotherapy appeared to be feasible for the majority of patients who developed severe chemotherapy- and/or radiotherapy-induced liver toxicity.

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national wilms tumor studies,hepatopathy,chemotherapy

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