Informal caregiver's socio demographic profile for community-dwelling women and men with mild to moderate Alzheimer's disease, compliance, and satisfaction to treatment: A post-hoc analysis of the AXEPT study.

In this post-hoc analysis of the AXEPT study, 855 patients were analyzed, 544 (63.6%) females. The mean (± SD) MMSE score in women vs men was 20.8 ± 2.6 vs. 21.2 ± 2.5; = 0.0087, and women were more likely affected by psychiatric disorders ( = 76, 14.0% women vs. = 21, 6.8% men; p = 0.0015). Men were mainly assisted by their wives ( = 207, 66.6%), women mainly by their daughters ( = 243, 44.7%) and only in a minority of cases by their husbands ( = 92, 16.9%). Women less frequently cohabited with their caregivers than men ( = 233, 43.1% vs. = 240, 77.9%, < 0.0001), and received less daily time of caregiving (mean (± SD): 10.0 ± 7.2 vs. 15.2 ± 8.2; < 0.0001). No gender differences were highlighted in compliance to treatment and caregiver satisfaction, while gender differences in caregiving were found at disadvantage of women affected by more severe cognitive and psychiatric conditions.